Postdoctoral fellow or research associate

Postdoctoral Fellow or Research Associate

Date Posted: Jul 5, 2022
Faculty Member: Xianxin Hua
Position Type: Other
Number of Slots : 2
School: Perelman School of Medicine
Organization: CB-Cancer Biology-Basic Sciences Dept

Description:

Postdoctoral and research associate positions are available immediately to develop novel cancer immunotherapy, i.e. chimeric antigen receptor (CAR)-expressing T cells, to eradicate human neuroendocrine tumors (NETs) and gastrointestinal cancers as well as acute myeloid leukemia (AML), and investigate the unique molecular mechanisms on how CAR constructs, including the binders and the signaling domains, improve the T cell antitumor activity to eliminate solid tumors.

Qualifications:

Postdoctoral and research associate positions are available immediately to develop novel cancer immunotherapy, i.e. chimeric antigen receptor (CAR)-expressing T cells, to eradicate human neuroendocrine tumors (NETs) and gastrointestinal cancers as well as acute myeloid leukemia (AML), and investigate the unique molecular mechanisms on how CAR constructs, including the binders and the signaling domains, improve the T cell antitumor activity to eliminate solid tumors. These positions require experience in molecular cell biology or immunology and ideally experience with various mouse tumor models and flow cytometry analysis. Experience in T cell biology is valuable. The candidates should have a Ph.D. or equivalent degree. Successful applicants will have rich opportunities to gain a broad range of cutting-edge knowledge and experience ranging from synthetic biology, genome wide CRISPRa screening, immunology, bioinformatics, immunotherapy models as well as bench side to bedside translational studies. They will have opportunities to write grant proposal and enjoy a vibrant and highly interactive environment integrating cancer biology, immunology, translational immunotherapy ongoing at Penn campus that promote their career advancement. Research work and directions can be found in the related published papers ( https://pubmed.ncbi.nlm.nih.gov/35314826/; https://pubmed.ncbi.nlm.nih.gov/31951650/ ).

More information:

https://www.med.upenn.edu/apps/faculty/index.php/g275/p10254
https://pubmed.ncbi.nlm.nih.gov/35314826/
https://pubmed.ncbi.nlm.nih.gov/31951650/

Contact:

University of Pennsylvania School of Medicine
Department of Cancer Biology
Abramson Family Cancer Research Institute (AFCRI)

Email: huax@pennmedicine.UPenn.edu

If interested, please apply: https://apptrkr.com/3215521

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