Research Specialist B/C

Research Specialist B/C

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn's distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America's Best Employers By State in 2021.

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The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

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Posted Job Title
Research Specialist B/C

Job Profile Title
Research Specialist B

Job Description Summary
Seeking a Research Specialist B/C to work as part of a translational HIV research lab, with a focus on understanding how HIV persists through antiretroviral therapy and how we can improve HIV cure strategies. The candidate will process human and animal biospecimens, perform HIV sequencing, cloning, and phenotypic testing, requiring both molecular virology and tissue culture skills. The position will require leading research projects in collaboration with the PI, as well as supervising and/or working with graduate and undergraduate students.
  • Laboratory oversight and management tasks including: training other lab technicians and undergraduates, maintenance of supplies, equipment and generated data.
  • Regulatory duties including: writing and management of standard operating procedures, maintaining compliance with regulatory standards, management of critical documents pertaining to the clinical study.
  • Research duties include:
    o Virus sequencing and sequence analysis, in collaboration with bioinformaticians.
    o HIV-1 env and full-length virus cloning
    o Virus isolate generation
    o Virus replication and entry experiments
  • Perform processing of human and animal biospecimens, including blood and tissues.
  • Perform molecular techniques including: PCR, DNA isolation from bacteria and viruses, restriction enzyme digestion, gel electrophoresis, DNA amplification by the polymerase chain reaction, DNA sequencing, assay development.
  • General laboratory duties including: reagent preparation, ordering supplies, basic lab cleaning and maintenance.
  • Present data at internal and external meetings
  • Maintaining a daily lab notebook
  • Organizing specimens in a laboratory inventory management system

    Job Description

    DUTIES:

    Molecular and Microbiology laboratory techniques - processing of biospecimens, RNA extraction, DNA synthesis, PCR, sequencing, molecular cloning, virus entry and replication experiments, virus isolate generation and validation. 40%

    Experimental design and analyses- Design experiments, interpret results, communicate results. 20%

    General Laboratory Duties-Inventory (order supplies), making reagents, oversees reagent storage/expiration, perform quality control and safety tasks, maintain equipment. 10%

    Record keeping and data analysis-Enter records into database, tracking study records, QA on data submitted. Attend weekly lab meetings and presenting data and progress. 20%

    Communicate and coordinate with outside collaborators for evaluating the use of new equipment and techniques. 5%

    Additional duties as assigned. 5%

    The Infectious Diseases Division is seeking a full time Research Specialist B/C to work as part of a translational HIV research lab, with a focus on understanding how HIV persists through antiretroviral therapy and how we can improve HIV cure strategies. The candidate will process human and animal biospecimens, perform HIV sequencing, cloning, and phenotypic testing, requiring both molecular virology and tissue culture skills. Under the supervision of the Principal Investigator, the RS C/B will also be responsible for various day-to-day study operations including maintaining study databases, compliance with all IRB and regulatory documentation, and assisting with the preparation of materials to disseminate study results as needed. Experienced candidates will have the opportunity to work closely with and provide supervision of graduate and undergraduate students based on experience and interest. The RS B/C should be able to work closely with external partners, such as collaborating scientists and laboratories.

    Research Specialist B:
    • Virus sequencing and sequence analysis, in collaboration with bioinformaticians.
    • HIV-1 env and full-length virus cloning
    • Virus isolate generation
    • Virus replication and entry experiments
    • Perform processing of human and animal biospecimens, including blood and tissues.
    • Perform molecular techniques including: PCR, DNA isolation from bacteria and viruses, restriction enzyme digestion, gel electrophoresis, DNA amplification by the polymerase chain reaction, DNA sequencing, assay development.
    • Perform sequence analyses and sequence data management
    • General laboratory duties including: reagent preparation, ordering supplies, basic lab cleaning and maintenance.
    • Present data at internal and external meetings
    • Maintaining a daily lab notebook
    • Organizing specimens in a laboratory inventory management system
    • Attend research team meetings

    Research Specialist C:
    • Perform all duties as listed above
    • Manage and oversee the work of students and research assistants
    • Maintain relationships and collaborate with external partners and community organizations
    • Maintain regulatory compliance and IRB documentation
    • Draft figures and contribute to manuscript and grant development


    QUALIFICATIONS: (Qualifications should clearly indicate those that are required and those that are preferred.)

    Research Specialist B: A Bachelor's degree and a minimum of 1 year research experience is required. Experience with molecular virology and sequencing is preferred. Strong interpersonal and communication skills required.

    Research Specialist C: A Bachelor's degree and 3-5 years of research experience is required. Master's degree preferred. Experience with molecular biology and sequencing. HIV research experience preferred, but not required. Strong computer skills are essential. Candidates must be detail-oriented with excellent communication and interpersonal skills including when working closely students; ability to multi-task; and flexibility to shift focus between multiple projects as needed.

    Position contingent upon funding.

    Job Location - City, State
    Philadelphia, Pennsylvania
    Research Specialist B

    Department / School
    Perelman School of Medicine

    Pay Range
    $37,220.00 - $56,087.33
    Salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, as well as internal and market factors and grade profile.

    Affirmative Action Statement
    Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

    Special Requirements
    Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

    University Benefits
    • Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family's health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.
    • Tuition: Take advantage of Penn's exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions.
    • Retirement: Penn offers generous retirement plans to help you save for your future. Penn's Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.
    • Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family-whatever your personal needs may be.
    • Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you're newly hired, you won't have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.
    • Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That's why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance.
    • Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally.
    • University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University's libraries and athletic facilities, or visit our arboretum and art galleries. There's always something going on at Penn, whether it's a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you're right in the middle of the excitement-and you and your family can enjoy many of these activities for free.
    • Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks.
    • Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.
    • Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements.
    • Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household.



    To learn more, please visit: https://www.hr.upenn.edu/PennHR/benefits-pay

    To apply, visit https://wd1.myworkdaysite.com/en-US/recruiting/upenn/careers-at-penn/job/Medical-School-Johnson-Pavilion---5th-Floor/Research-Specialist-B-C_JR00042287-2

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